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Pseudolymphoma

MedGen UID:: 67450
•Concept ID:: C0221269
•: Neoplastic Process

Synonyms:	Hyperplasia, Reactive Lymphoid; Hyperplasias, Reactive Lymphoid; Lymphocytoma; Lymphocytomas; Lymphoid Hyperplasia, Reactive; Lymphoid Hyperplasias, Reactive; Pseudolymphomas; Reactive Lymphoid Hyperplasia; Reactive Lymphoid Hyperplasias
SNOMED CT:	Benign lymphoid hyperplasia (19750001); Pseudolymphoma (19750001); Reactive lymphoid hyperplasia (43961000)

Monarch Initiative:	MONDO:0043959

Definition

A neoplastic process that resembles a malignant lymphoma, but has a benign course. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPseudolymphoma

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Neoplasm by Obsolete Classification
        Hematopoietic and Lymphoid Neoplasm (Antiquated)
        Pseudolymphoma
        Cervical Florid Reactive Lymphoid Hyperplasia
        Conjunctival Reactive Lymphoid Hyperplasia
        Reactive lymphoid hyperplasia of lacrimal gland

Professional guidelines

PubMed

Treatment of Cutaneous Pseudolymphoma: A Systematic Review.

Miguel D, Peckruhn M, Elsner P
Acta Derm Venereol 2018 Mar 13;98(3):310-317. doi: 10.2340/00015555-2841. PMID: 29136262

CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators.

Kempf W
J Cutan Pathol 2006 Feb;33 Suppl 1:58-70. doi: 10.1111/j.0303-6987.2006.00548.x. PMID: 16412214

Cutaneous pseudolymphomas: classification and differential diagnosis.

Rijlaarsdam JU, Willemze R
Semin Dermatol 1994 Sep;13(3):187-96. PMID: 7986687

See all (13)

Recent clinical studies

Etiology

Cutaneous reactive B-cell lymphoid proliferations.

Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.

Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707

Cutaneous Pseudolymphoma.

Mitteldorf C, Kempf W
Surg Pathol Clin 2017 Jun;10(2):455-476. Epub 2017 Mar 22 doi: 10.1016/j.path.2017.01.002. PMID: 28477891

Tattoos: dermatological complications.

Kazandjieva J, Tsankov N
Clin Dermatol 2007 Jul-Aug;25(4):375-82. doi: 10.1016/j.clindermatol.2007.05.012. PMID: 17697920

Cutaneous pseudolymphomas.

Ploysangam T, Breneman DL, Mutasim DF
J Am Acad Dermatol 1998 Jun;38(6 Pt 1):877-95; quiz 896-7. doi: 10.1016/s0190-9622(98)70154-9. PMID: 9631994

See all (258)

Diagnosis

Pseudolymphomatous folliculitis.

Roque Quintana B, Peñate Y, Montenegro Dámaso T
Dermatol Online J 2020 May 15;26(5) PMID: 32621704

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.

Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707

Cutaneous Pseudolymphoma.

Mitteldorf C, Kempf W
Surg Pathol Clin 2017 Jun;10(2):455-476. Epub 2017 Mar 22 doi: 10.1016/j.path.2017.01.002. PMID: 28477891

Lymphocytic Interstitial Pneumonia.

Panchabhai TS, Farver C, Highland KB
Clin Chest Med 2016 Sep;37(3):463-74. Epub 2016 Jun 25 doi: 10.1016/j.ccm.2016.04.009. PMID: 27514593

Cutaneous Pseudolymphomas.

Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134

See all (791)

Therapy

Borrelial Lymphocytoma.

Rezazadegan R, Koushk-Jalali B, Kreuter A
Dtsch Arztebl Int 2022 May 20;119(20):369. doi: 10.3238/arztebl.m2022.0015. PMID: 36017988 Free PMC Article

Cutaneous pseudolymphoma-A review on the spectrum and a proposal for a new classification.

Mitteldorf C, Kempf W
J Cutan Pathol 2020 Jan;47(1):76-97. Epub 2019 Jul 31 doi: 10.1111/cup.13532. PMID: 31237707

HIV-Associated Psoriasis.

Queirós N, Torres T
Actas Dermosifiliogr (Engl Ed) 2018 May;109(4):303-311. Epub 2018 Feb 1 doi: 10.1016/j.ad.2017.09.014. PMID: 29361272

Lymphocytic Interstitial Pneumonia.

Panchabhai TS, Farver C, Highland KB
Clin Chest Med 2016 Sep;37(3):463-74. Epub 2016 Jun 25 doi: 10.1016/j.ccm.2016.04.009. PMID: 27514593

Cutaneous Pseudolymphomas.

Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134

See all (297)

Prognosis

Pseudolymphomatous Atypical Fibroxanthoma.

Garcia Castro R, Viñolas-Cuadros A, Moyano-Bueno D, Conde-Ferreiros A, Cardeñoso E, Santos-Briz A
Am J Dermatopathol 2020 Dec;42(12):972-976. doi: 10.1097/DAD.0000000000001761. PMID: 32769551

EBV-Associated Lymphoproliferative Disorders: Update in Classification.

Rezk SA, Weiss LM
Surg Pathol Clin 2019 Sep;12(3):745-770. doi: 10.1016/j.path.2019.03.002. PMID: 31352986

Dermoscopy of Lymphomas and Pseudolymphomas.

Bombonato C, Pampena R, Lallas A, Giovanni P, Longo C
Dermatol Clin 2018 Oct;36(4):377-388. Epub 2018 Aug 14 doi: 10.1016/j.det.2018.05.005. PMID: 30201147

Cutaneous Pseudolymphomas.

Romero-Pérez D, Blanes Martínez M, Encabo-Durán B
Actas Dermosifiliogr 2016 Oct;107(8):640-51. Epub 2016 Jun 8 doi: 10.1016/j.ad.2016.05.003. PMID: 27289134

Cutaneous lymphoid hyperplasias.

Gilliam AC, Wood GS
Semin Cutan Med Surg 2000 Jun;19(2):133-41. doi: 10.1016/s1085-5629(00)80011-5. PMID: 10892716

See all (240)

Clinical prediction guides

Iron induces B cell pyroptosis through Tom20-Bax-caspase-gasdermin E signaling to promote inflammation post-spinal cord injury.

Wu C, Wang L, Chen S, Shi L, Liu M, Tu P, Sun J, Zhao R, Zhang Y, Wang J, Pan Y, Ma Y, Guo Y
J Neuroinflammation 2023 Jul 22;20(1):171. doi: 10.1186/s12974-023-02848-0. PMID: 37480037 Free PMC Article

Cutaneous reactive B-cell lymphoid proliferations.

Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820

Pseudolymphomatous Atypical Fibroxanthoma.

Garcia Castro R, Viñolas-Cuadros A, Moyano-Bueno D, Conde-Ferreiros A, Cardeñoso E, Santos-Briz A
Am J Dermatopathol 2020 Dec;42(12):972-976. doi: 10.1097/DAD.0000000000001761. PMID: 32769551

Cutaneous targets in drug-induced reactions.

Filotico R, Mastrandrea V
G Ital Dermatol Venereol 2014 Apr;149(2):227-35. PMID: 24819644

Cutaneous lymphoid hyperplasias.

Gilliam AC, Wood GS
Semin Cutan Med Surg 2000 Jun;19(2):133-41. doi: 10.1016/s1085-5629(00)80011-5. PMID: 10892716

See all (185)

Recent systematic reviews

Drug-induced cutaneous pseudolymphoma: A systematic review of the literature.

Etesami I, Kalantari Y, Tavakolpour S, Mahmoudi H, Daneshpazhooh M
Australas J Dermatol 2023 Feb;64(1):41-49. Epub 2022 Nov 4 doi: 10.1111/ajd.13951. PMID: 36331821

Clinical features, natural history and outcomes of pseudolymphoma of liver: A case-series and systematic review.

Jiang W, Wu D, Li Q, Liu CH, Zeng Q, Chen E, Lu C, Tang H
Asian J Surg 2023 Feb;46(2):841-849. Epub 2022 Sep 16 doi: 10.1016/j.asjsur.2022.08.113. PMID: 36123208

Treatment of Cutaneous Pseudolymphoma: A Systematic Review.

Miguel D, Peckruhn M, Elsner P
Acta Derm Venereol 2018 Mar 13;98(3):310-317. doi: 10.2340/00015555-2841. PMID: 29136262

Atypical presentations of cutaneous leishmaniasis: A systematic review.

Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427

See all (4)

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Pseudolymphoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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